Appleton began the Cheshire Building Society Cricket Alliance Division Two season in fine style.
Their comfortable five-wicket win came after tight bowling had restricted Disley to 125 runs.
The pick of the bowlers was Duane Jones, who returned figures of 2 for 4 off 10 overs.
A fine 51 by Antony Hurst sent Appleton on their way to success.
Appleton's second XI began with a draw at home to Disley and were led by Pepper's fine 43.
Appleton set an imposing total of 165 to win.
Disley showed no ambition from the start and settled for a draw.
Appleton's best bowling return came from Lee Stoll with figures of 3 for 25.
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